Discover Your Perfect Panama Vacation Homes

Best Vacation Homes in Panama

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7.0 (6 Reviews)
Apartment
Flat & Residence Premium
  • Air Conditioner
  • Parking
  • Pet Friendly
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Why Choose Rent By Owner for your Panama Vacation Rental Homes?

What makes our Vacation Rentals special?

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Verified Listings
Book with confidence knowing every property meets our quality and safety standards.
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Unbeatable Value
Enjoy competitive pricing with no hidden fees, providing exceptional value for every stay.
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Diverse Options
From cozy cabins to luxurious villas, find a rental that suits your style and needs.

Popular Areas for Panama Vacation Rentals

Where are the best neighborhoods to stay in Panama?

When exploring Panama, your choice of neighborhood can significantly enhance your stay in this vibrant country. The neighborhoods around Panama City offer a mix of modern amenities and local charm, making them ideal for travelers seeking comfort and convenience. If you prefer a lively atmosphere with easy access to key attractions, staying in the central districts provides a seamless experience. For those looking for a more relaxed environment, quieter areas surrounding the city still deliver excellent amenities and authentic Panamanian culture. Whichever neighborhood you choose, finding the right vacation rental in Panama will ensure a memorable visit filled with comfort and ease.

Santo Amaro

In Santo Amaro, you can enjoy a peaceful atmosphere while being conveniently close to local amenities, making it an ideal choice for those seeking comfortable vacation rentals in this part of the region. This neighborhood offers a relaxed environment perfect for relaxing stays during your visit.

View 70+ Rentals in Santo Amaro

Jardim Aeroporto

Jardim Aeroporto provides excellent connectivity and easy access to transportation routes, making it a practical base for exploring the area. Choosing vacation rentals here ensures a convenient and comfortable stay in this vibrant sector of the region.

View 195+ Rentals in Jardim Aeroporto

Santo Antonio

Santo Antonio features a welcoming community with a variety of local services, offering an authentic experience within this part of the region. Vacation rentals in this neighborhood provide both comfort and convenience for your trip.

View 88+ Rentals in Santo Antonio

Popular

Popular is known for its lively atmosphere and proximity to key city areas, making it a strategic choice for travelers looking to immerse themselves in the local culture. Here, vacation rentals allow you to enjoy easy access to the area's main attractions and amenities.

View 178+ Rentals in Popular

Best Times to Visit Panama

When should you plan your Vacation Rentals stay?

To make the most of your stay, consider visiting during the region’s dry season when the weather is ideal for exploring and outdoor activities, ensuring your vacation in this part of Brazil is both enjoyable and memorable.

Peak Season Highlights

spring
December to March

During these months, the area experiences its warmest and most humid weather, making it ideal for enjoying the region's outdoor activities and beaches.

Average Temperature Daytime: 30°C - Nighttime: 22°C
spring
June to August

This period marks the peak of the dry season, offering sunny days perfect for exploring and outdoor adventures in the region.

Average Temperature Daytime: 28°C - Nighttime: 20°C

Off-Season Highlights

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April to May

These shoulder months see a slight decrease in rainfall and temperatures, providing a quieter time to enjoy the area's natural beauty without the crowds.

Average Temperature Daytime: 27°C - Nighttime: 19°C
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September to November

The region experiences increased rain and reduced tourist activity during these months, making it an excellent time for budget-friendly stays and exploring at a relaxed pace.

Average Temperature Daytime: 26°C - Nighttime: 18°C

Weekly Weather Forecast for Panama

How to Book Your Panama Vacation Rental Home

What's our booking process?

Our platform allows you to browse a curated selection of vacation rentals. Once you find the ideal property, you’ll be redirected to a trusted booking partner to complete your reservation securely.

Booking Steps

01

Search Properties

Use our filters to find the right property that fits your needs.
02

Select a Rental

Click on your preferred listing to view details, amenities, and pricing.
03

Book Online

Follow the link to finalize your reservation directly on the partner’s website.

Explore and book the perfect rental in Panama

More Top-Rated Vacation Rentals in Panama Area

Common Vacation Rentals Amenities

What amenities can you expect?

Our Vacation Rentals are designed to offer all the comforts of home, often with added perks to make your stay unforgettable. Here’s some common amenities to look forward to:

Indoor Features

  • Fully-equipped kitchens with modern appliances
  • Comfortable living areas with flat-screen TVs
  • Free Wi-Fi for staying connected
  • Air conditioning and heating for year-round comfort
  • In-unit washers and dryers for convenience
  • Luxurious bedrooms with premium bedding
  • Spa-like bathrooms with soaking tubs or walk-in showers

Outdoor Amenities

  • Enjoy a refreshing swimming pool to unwind after exploring the region.
  • Relish outdoor dining areas perfect for savoring local flavors in the open air.
  • Take advantage of landscaped gardens and green spaces for relaxation and leisure.
  • Make use of shaded patios or verandas to comfortably enjoy the surroundings.
  • Experience outdoor barbecue facilities ideal for hosting gatherings with friends or family.
  • Explore nearby walking or hiking trails that showcase the area's natural beauty.
  • Benefit from secure parking areas to conveniently explore the destination at your own pace.

Top Attractions Around Panama

What attractions are nearby?

Within this vibrant area, you can enjoy a variety of outdoor activities and explore local attractions that highlight the natural beauty and cultural richness of the region surrounding your vacation rental in Panama, Campo Grande, Central - West Region, Brazil.

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Family Activities

  • Panama Canal Tour: You can explore the world-famous canal that demonstrates the impressive engineering marvels of this region, offering an educational and fun experience for the whole family.
  • Biomuseo Visit: Discover the rich biodiversity of the area through engaging exhibits that highlight the region’s ecological importance and cultural heritage.
  • Cinta Costera Park: Enjoy outdoor activities at this scenic waterfront park perfect for family picnics, cycling, or just relaxing while taking in views of the city skyline.
  • Gatun Lake Excursion: Embark on a boat trip across this expansive lake, where you can observe local wildlife and learn about the region's significance in Panama's history.
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Adult Activities

  • Exploring local art galleries and cultural centers: Discover the vibrant arts scene that reflects the region’s rich heritage and contemporary creativity.
  • Enjoying nature walks in nearby national parks: Immerse yourself in the lush landscapes and tranquil surroundings that highlight this area's natural beauty.
  • Savoring regional cuisine at local restaurants: Experience the authentic flavors and culinary traditions that make dining here a memorable adventure.
  • Visiting historical sites and landmarks: Delve into the area's history by exploring its well-preserved monuments and cultural attractions.

Panama Travel Tips

How Can You Make the Most of Your Stay?

  • Plan Ahead: Research the local customs and popular activities in the area to optimize your stay and fully experience what this destination offers.
  • Choose Prime Locations: When booking vacation rentals, select properties close to major attractions or transportation hubs to save time and enhance convenience.
  • Experience Local Flavors: Take the opportunity to explore local markets and eateries near your accommodation for authentic regional cuisine.
  • Stay Connected: Ensure your rental provides reliable Wi-Fi to keep in touch with loved ones and access useful travel information during your visit.

Transportation Options

  • Local Bus Services: Efficient and affordable buses connect various parts of the area, making it easy for you to explore this destination without hassle.
  • Taxis and Ride-Sharing: Convenient taxi and ride-sharing options are widely available, offering quick transportation around the region for your comfort.
  • Rental Cars: Renting a car provides the flexibility to discover more remote attractions and navigate the area at your own pace.
  • Private Shuttle Services: Private shuttle services offer a reliable way to travel directly to key destinations within the region, ensuring a seamless experience during your stay.

Local Customs Options

  • Indigenous Traditions: Respect the indigenous customs that influence local art, crafts, and community gatherings here in the region.
  • Festivals and Celebrations: Participate or observe colorful festivals that showcase the area's vibrant cultural heritage and social spirit.
  • Timely Greetings and Politeness: Engage with friendly greetings and polite gestures that are customary in social interactions within the area.
  • Local Cuisine Etiquette: Appreciate traditional dining manners and local food practices that reflect the region's culinary identity.

Frequently Asked Questions About Panama?

1. What are the top vacation rentals in Panama?

There are a lot of options in Panama. If you plan on staying in the Panama area, consider making a reservation for a few nights at one of these properties as these have been rated the Top Vacation Rentals in Panama:

2. How many vacation rentals have private pools in Panama?

There are 46 vacation rentals with private pools near Panama. Top-rated RBO homes that have access to a swimming pool include:

3. Which vacation homes in Panama are best for families?

If you are looking for a family-friendly vacation home in Panama, check out one of the following properties as all are highly-rated places to stay with excellent review for families or groups staying in Panama:

4. How many Rentbyowner vacation rentals are available in Panama?

Currently, the total number of properties listed by Rent By Owner in 2025 is over 326 in the Panama area, and still counting. By aggregating listings from multiple websites, Rent By Owner offers an immense amount of choice of the best RBO properties in Panama. 

5. What is the cancellation policy for vacation rentals in this area?

Cancellation policies vary by property. It is important to review the specific listing details and contact the owner directly to understand the terms before booking.

6. How do I secure my reservation at a vacation rental in this destination?

Reservations are typically secured through the booking platform by following the outlined process and completing the payment as instructed. Confirm all details with the owner if needed to ensure your stay is confirmed.

7. Are there any additional fees I should be aware of when booking a vacation rental here?

Additional fees such as cleaning or service charges may apply depending on the property. Be sure to read the listing carefully and reach out to the owner if you have questions about extra costs.

8. What amenities can I expect from vacation rentals in this region?

Amenities vary by property, but many offer essentials like Wi-Fi, air conditioning, and fully equipped kitchens. Review the listing details for specific features available at your chosen rental.

9. Is it possible to modify or cancel my booking after confirming it?

Modification and cancellation policies depend on the individual property. Check the listing’s cancellation and change policies, and contact the owner directly for assistance with adjustments to your reservation.